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The Endocannabinoid System? When was the endocannabinoid system discovered?

 The Endocannabinoid System? When was the endocannabinoid system discovered?

The answer to that question started to unfold in 1992, when the first endocannabinoid was discovered. Anandamide was the first, naturally occurring endogenous cannabinoid, or endocannabinoid. It was found by Raphael Mechoulam as well as NIMH researchers William Devane and Dr. Lumir Hanus.  All cannabinoids, including CBD, produce effects in the body by attaching to certain receptors. The human body produces certain cannabinoids on its own. ... CB1 receptors are present throughout the body, but many are in the brain.

 What you may not realise, however, is that this follows from the fact that the human body actually produces its own endogenous cannabinoids: natural equivalents of the compounds found in the cannabis plant, such as THC (tetrahydrocannabinol) and CBD (cannabidiol).

The endocannabinoid system is a biological system composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the vertebrate central nervous system and peripheral nervous system.

 

   

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